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The deadliest skin cancer, melanoma, can affect the liver and brain in its later stages, as happened to former President Jimmy Carter, explains The deadliest skin cancer, melanoma, can affect the liver and brain in its later stages, as happened to former President Jimmy Carter, explains Ramsay Farah, MD Ramsay Farah, MD, division chief of, division chief of dermatology dermatology at Upstate. Caused by pigment-producing cells called melanocytes, melanoma is best treated when caught early, says Farah, who notes the significance of irregular moles and the need for regular skin exams. Farah also details Carter's cutting-edge treatment, which awakens the body‘s immune system to fight the melanoma. at Upstate. Caused by pigment-producing cells called melanocytes, melanoma is best treated when caught early, says Farah, who notes the significance of irregular moles and the need for regular skin exams. Farah also details Carter's cutting-edge treatment, which awakens the body‘s immune system to fight the melanoma.